KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HGS
All Species:
35.91
Human Site:
S775
Identified Species:
71.82
UniProt:
O14964
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14964
NP_004703.1
777
86192
S775
G
S
E
A
Q
L
I
S
F
D
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_511742
777
85768
S775
G
S
E
A
Q
L
I
S
F
D
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001111673
777
86015
S775
G
S
E
A
Q
L
I
S
F
D
_
_
_
_
_
Dog
Lupus familis
XP_540486
782
86005
S780
G
S
E
A
Q
L
I
S
F
D
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q99LI8
775
85996
S773
G
S
E
A
Q
L
I
S
F
D
_
_
_
_
_
Rat
Rattus norvegicus
Q9JJ50
776
86228
S774
G
N
E
T
Q
L
I
S
F
D
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083588
751
84100
S749
R
S
E
A
Q
L
I
S
F
D
_
_
_
_
_
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X8
760
85396
S758
P
A
T
A
E
L
I
S
F
D
_
_
_
_
_
Honey Bee
Apis mellifera
XP_393989
830
92147
S828
P
E
T
A
E
L
I
S
F
D
_
_
_
_
_
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783582
784
87687
S782
Q
Q
E
G
T
L
I
S
F
E
_
_
_
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40343
622
70927
Red Bread Mold
Neurospora crassa
Q7RZJ2
724
79729
Conservation
Percent
Protein Identity:
100
95.5
98.8
92.3
N.A.
93.3
93.4
N.A.
N.A.
N.A.
80
N.A.
N.A.
41.7
47.7
N.A.
49.4
Protein Similarity:
100
96.6
98.9
94.2
N.A.
95.6
95.6
N.A.
N.A.
N.A.
87.5
N.A.
N.A.
55.7
60.9
N.A.
61.3
P-Site Identity:
100
100
100
100
N.A.
100
80
N.A.
N.A.
N.A.
90
N.A.
N.A.
60
60
N.A.
50
P-Site Similarity:
100
100
100
100
N.A.
100
90
N.A.
N.A.
N.A.
90
N.A.
N.A.
80
70
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
24.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
41
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
67
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
75
0
0
0
0
0
% D
% Glu:
0
9
67
0
17
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
84
0
0
0
0
0
0
% F
% Gly:
50
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
84
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
84
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
9
0
0
59
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
50
0
0
0
0
0
84
0
0
0
0
0
0
0
% S
% Thr:
0
0
17
9
9
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
84
84
84
84
84
% _